Different Diclofenac diethylamine formulations have similar pain relief and tolerability in acute ankle sprain
Diclofenac diethylamine (DDEA) 2.32% gel BID and Diclofenac diethylamine (DDEA) 1.16% gel QID is equally efficient for acute ankle sprain suggests a new study published in the BMC Musculoskeletal DisordersDiclofenac diethylamine (DDEA) gel has demonstrated efficacy for treatment of ankle sprains in both the 1.16% four-times-daily (QID) and 2.32% twice-daily (BID) formulations. The objective...
Diclofenac diethylamine (DDEA) 2.32% gel BID and Diclofenac diethylamine (DDEA) 1.16% gel QID is equally efficient for acute ankle sprain suggests a new study published in the BMC Musculoskeletal Disorders
Diclofenac diethylamine (DDEA) gel has demonstrated efficacy for treatment of ankle sprains in both the 1.16% four-times-daily (QID) and 2.32% twice-daily (BID) formulations. The objective of this study was to compare, for the first time, the efficacy of DDEA 2.32% gel BID and DDEA 1.16% gel QID.
DDEA 2.32% gel BID offers a convenient alternative to DDEA 1.16% gel QID, with similar pain reduction and relief, anti-inflammatory effects, and tolerability.
Reference:
Yin, F., Ma, J., Xiao, H. et al. Randomized, double-blind, noninferiority study of diclofenac diethylamine 2.32% gel applied twice daily versus diclofenac diethylamine 1.16% gel applied four times daily in patients with acute ankle sprain. BMC Musculoskelet Disord 23, 1125 (2022). https://doi.org/10.1186/s12891-022-06077-z
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