Duloxetine reduces pain and boosts mood among patients with Chronic musculoskeletal pain
In a recent study, researchers have reported the role of Duloxetine in reducing the patient's pain level, improving mood and life quality a patient's mood and quality of life, and delaying the progression of chronic musculoskeletal diseases like knee osteoarthritis and fibromyalgia syndrome.
According to the researchers, Duloxetine is efficacious in managing CMP patients.
Chronic musculoskeletal pain (CMP) is a complex condition and is majorly faced by older people affecting normal work and life. Long-term chronic pain affects patients’ psychology and mood and may induce depression, anxiety, or other diseases. The treatment goal is to relieve pain.
Clinical studies have shown that opioids can play a role in antidepressant treatment by modulating the neurotransmitter system, but side effects and dependence cannot be ignored.
Duloxetine, a norepinephrine and serotonin reuptake inhibitor (NSRI), can play an antidepressant and analgesic role.
In the present study, researchers found that the depression symptoms of patients with CMP treated with Duloxetine are reduced, and it also improves the mood index. Treated patients are more active in normal interpersonal communication and work life than patients in the placebo control group. The main purpose of the study was to evaluate the efficacy and safety of Duloxetine in treating CMP using data from PubMed, Web of Science, Embase, and Cochrane Library.
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