High disability early in RA tied to increased mortality risk, finds study
Canada: Higher self-reported disability and disease activity score (DAS) at 1 year significantly increased all‐cause mortality in patients with early rheumatoid arthritis (ERA), suggests a recent study published in the journal Arthritis & Rheumatology.
Safoora Fatima, University of Western Ontario, London, Ontario, Canada, and colleagues assessed the association of higher self‐reported disability (high HAQ) with hospitalizations and mortality in early rheumatoid arthritis.
It included 1724 patients (mean age 55 years; 72% female) with ERA (symptoms <1 year) who were enrolled in the Canadian Early Arthritis Cohort (CATCH) who initiated DMARDs and had completed HAQ data at baseline and 1 year follow up. Discrete‐time proportional hazards models were used for the estimation of crude and multi‐adjusted associations between HAQ at baseline and 1 year, respectively, with all‐cause mortality in each year of follow up.
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