High femoral offset has 3.7-fold increased probability for aseptic femoral component loosening: study

Key findings of the study were:

• Two thousand four hundred fifty-nine THA could be included, containing 14 THA (0.6%) with aseptic femoral component loosening.

• The AL group contained 11 hFO combinations (78.6%), whereas in the nAL group, 1315 hFO combinations (53.8%) were used.

• Subgroup analysis showed significant difference between two groups for hFO combinations (p = 0.014), age (p = 0.002), NSAR (p = 0.001), and bilateral THA on same day (p = 0.001).

• The multiple logistic regression analysis showed that hFO combination was the only variable for increased probability of aseptic loosening (OR, 3.7; p = 0.04).

The authors concluded – “High femoral offset combinations, formed by lateralized stems or large femoral head lengths in our collective of standard straight stems implanted by an anterior approach, show a 3.7-fold increased probability for aseptic femoral component loosening. Adjustment of the postoperative protocol may be considered in these cases to ensure proper stem ingrowth.”

Further reading:

High femoral offset as a risk factor for aseptic femoral component loosening in cementless primary total hip arthroplasty Lukas Jud et al International Orthopaedics (2024) 48:1217–1224 https://doi.org/10.1007/s00264-024-06116-5