Idiopathic inflammatory myopathy increases risk of CV events
UK: Idiopathic inflammatory myopathy (IIM) patients are at an increased risk of cardiovascular (CV) events similar to those found in rheumatoid arthritis (RA) with a greater excess risk during the first 5 years following the diagnosis, finds a recent study.
The study, published in the journal Clinical Rheumatology, calls for the development of guidelines on the assessment and management in IIM to take into account cardiovascular risk in IIM. This would help in reducing otherwise high mortality in IIM patients despite immunosuppressive treatment, with cardiac disease being a major cause of death.
Several connective tissue diseases and chronic inflammatory disorders are known to increase cardiovascular disease (CVD) risk secondary to accelerated atherosclerosis. Traditional risk factors for atherosclerotic vascular disease do not fully explain this increased CVD risk. Chronic systemic inflammation is thought to play an important role in accelerating the atherosclerotic processes.
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