Platelet-rich plasma improves healing of acute patellar tendon defect if injected early after injury: Study

The inflammatory condition was exaggerated in groups D and E. Load at failure was higher in the non-injected side of groups D and E, while there was no significant difference between the right and left legs of the three groups A, B and C. In other word, groups with a single PRP injection were more resistant to the increasing load compared to the groups with multiple PRP injections. PRP improves tendon healing if injected early after injury, while its injection after the initial phase of injury hampers tendon healing. In addition, a single PRP injection seems to be more effective than multiple PRP injection. Therefore, in cases where PRP injection is indicated for tendon repair, such as acute tendon injury, we recommend using a single PRP injection during tendon repair surgery.

Reference:

Ghaderi, M.T., Momenzadeh, O.R., Jaberi, F.M. et al. Effect of a single versus serial platelet-rich plasma injection on acute patellar tendon defect healing: an experimental study. BMC Musculoskelet Disord 25, 684 (2024). https://doi.org/10.1186/s12891-024-07804-4

Keywords:

Platelet-rich, plasma, improves, healing, acute, patellar, tendon, defect, injected, early, after, injury, study, Ghaderi, M.T., Momenzadeh, O.R., Jaberi, F.M, Platelet-rich plasma, Tendon defect, Patellar tendon, Rabbit model, Knee, BMC Musculoskeletal Disorders