Short-term Prednisone therapy reduces disease severity in newly diagnosed RA patients: Study
Temporary use of low dose prednisone monotherapy leads to disease remission and improved clinical severity of the majority of newly diagnosed patients with rheumatoid arthritis (RA), suggests a study published in the Adv Rheumatol
The ACR/EULAR recommendations endorse the use of glucocorticoids (GCs) for rheumatoid arthritis (RA) patients' flares and as a bridge to a DMARD. However, the recommendation of low dose short-term monotherapy with glucocorticoids (GCs) remains open to the discretion of the clinician.
A group of researchers from U.S.A conducted a study to assess whether short-term use of low dose prednisone monotherapy was effective in inducing remission in newly diagnosed for rheumatoid arthritis (RA).
The researchers performed a retrospective analysis of patients newly diagnosed with rheumatoid arthritis (RA) at a Community Health Center in North Dakota was performed based on the ACR/EULAR RA classification criteria. Demographic and clinical data were abstracted from patients' medical charts. Patients treated with (< 10 mg/day) of prednisone up to 6 months were included. Response to prednisone was analyzed according to pre- and post-treatment DAS28-ESR score and EULAR response criteria.
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