Surgical plating not superior to closed reduction for wrist fractures in elders;JAMA
A recent clinical trial titled 'The Combined Randomised and Observational Study of Surgery for Fractures in the Distal Radius in the Elderly', (CROSSFIRE) ,found no between-group differences in improvement in wrist pain or function at 12 months from VLP fixation over CR for displaced distal radius fractures in older people. The research findings have been put forth in JAMA Surgery.
The burden of injury and costs of wrist fractures are substantial. Surgical treatment became popular without strong supporting evidence.
Researchers undertook the current study to assess whether current surgical treatment for displaced distal radius fractures provided better patient-reported wrist pain and function than nonsurgical treatment in patients 60 years and older.
The study was designed as a multicenter randomized clinical trial and parallel observational study, with 300 eligible patients were screened from 19 centers in Australia and New Zealand from December 1, 2016, until December 31, 2018. A total of 166 participants were randomized to surgical or nonsurgical treatment and followed up at 3 and 12 months by blinded assessors. Those 134 individuals who declined randomization were included in a parallel observational cohort with the same treatment options and follow-up. The primary analysis was intention to treat; sensitivity analyses included as-treated and per-protocol analyses.
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