Systemic inflammation and malnutrition increased the risk of rheumatoid arthritis, finds study
A new study published in the journal of Clinical Rheumatology showed that high levels of systemic inflammation and malnutrition were both independent risk factors for rheumatoid arthritis (RA) patients' prognosis, and their co-occurrence can worsen the prognosis even more.
The cause of rheumatoid arthritis (RA), a chronic inflammatory illness mediated by the immune system, remains uncertain. It has a significant impact on the joints and is linked to disability, multimorbidity, a lower life expectancy, and a greater financial, social, and health cost when left untreated. Although it can start at any point in life, its frequency rises with age. According to recent research, elderly people had worse health outcomes and more severe RA.
Because of their weakened health, elderly RA patients could receive less intense therapy and be prescribed less biologics and conventional synthetic disease-modifying antirheumatic medications (csDMARDs), which might have a greater detrimental effect on their health. People with RA often suffer from malnutrition and systemic inflammation. The combined effects of inflammatory and nutritional levels on all-cause mortality in RA patients, however, have not been well investigated in research. Thus, Zhuang Ma and team investigated to look into these possible correlations.
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