Vitamin C intake after total knee arthroplasty may lower complex regional pain syndrome
A recent study conducted by Jacques and team showed that consuming 1 gram of vitamin C daily for 40 days post total knee arthroplasty (TKA) may decrease pain occurrence and lower the risk of complex regional pain syndrome (CRPS). The findings were published in International Orthopaedics.
The research involved 469 participants, comprising 168 men and 301 women, with an average age of 68.6 years (ranging from 40 to 93 years). The population was divided into two groups: one eligible for randomization, consisting of 292 patients who underwent surgery between January 2018 and July 2019, and a historical group of 177 individuals who had surgery between January 2016 and December 2017.
The prospective analysis compared 153 participants in the vitamin C group with 139 participants in the control group, while retrospective analysis was applied to assess the 177 individuals in the historical group. All participants underwent the same surgical technique performed by one of three surgeons, each with over 5 years of experience using the identical approach. Uniform TKA implants, incisions, and post-operative protocols were employed for all participants. Evaluation occurred at consistent post-operative intervals: at 12 days, 3 months, 6 months, and annually thereafter.
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