Weight fluctuation tied to advese CV events in Rheumatoid Arthritis
Researchers have found recent changes and high variability in weight that may help in predicting cardiovascular events in patients suffering from Rheumatoid Arthritis, particularly those who are thin, in a recent study published in the Journal of Arthritis Care and Research.
Fluctuations in weight have been linked to cardiovascular (CV) outcomes in the general population. "We evaluated whether weight fluctuation was independently predictive of CV events in patients with rheumatoid arthritis (RA)", describes Joshua F Baker from the Philadelphia VA Medical Center, Philadelphia, PA, USA.
Baker and colleagues studied a total of 31,381 participants, all of whom had Rheumatoid Arthritis. The data was collected from the Corrona registry. Weight change was categorized as a loss of ≥10%, loss of 5-10%, stable, gain of 5-10%, and gain of ≥10%. The authors further categorized patients by quintile of variability in weight in prior observation periods. Cox proportional hazard models explored independent associations between time-varying weight change and weight variability and risk of CV events before and after adjusting for CV risk factors, RA disease features, and disability.
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