Weight Loss-Associated Bone Loss Persists Despite Weighted Vest or Resistance Training: JAMA
Researchers have discovered in a 12-month randomized clinical trial that older adults with obesity experienced bone loss associated with weight loss, regardless of whether they engaged in resistance training or used a weighted vest. The study highlights the challenge of preserving bone health during weight reduction. The study was published in JAMA Network by Kristen M. and colleagues.
Weight loss in the elderly has traditionally been linked to reduced bone mass, an effect increasing the risk of fracture, especially in weight-bearing bones such as the hip. Tissue in the bones is very sensitive to stress caused by movement, and researchers were curious to see if external replacement of lost weight with weighted vests would preserve bone density. The main aim of this research was to contrast the impact of three interventions on bone: calorie-restricted weight loss alone (WL), weight loss with weighted vest use (WL+VEST), and weight loss with progressive resistance training (WL+RT).
This randomized clinical trial was performed at an academic medical center between September 1, 2019, and April 30, 2024. The study enrolled 150 older adults (mean age: 66.4 years; 74.7% female), all with obesity (mean BMI: 33.6), who were equally randomized to three intervention arms.
WL Group: Was given dietary intervention for 10% weight loss with proper intake of calcium, vitamin D, and protein.
WL+VEST Group: Followed the same diet regimen along with wearing a weighted vest for 8 hours per day, with weights being added incrementally to equate up to 10% of lost total body weight.
WL+RT Group: Fetched the diet regimen along with undergoing supervised progressive resistance training sessions, three times per week.
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