22 Percent of Indian Children with Diabetic Ketoacidosis Develop Kidney Injury, Reveals Hospital-Based Study
India: A recent study published in Apollo Medicine highlights a concerning complication in pediatric patients with diabetic ketoacidosis (DKA)-the development of acute kidney injury (AKI). Conducted by Dr. Satish Tadakanahalli and his team from the Department of Paediatrics at SDM College of Medical Sciences and Hospital, Shri Dharmasthala Manjunatheshwara University, the study found that nearly 23% of children admitted with DKA developed AKI, significantly prolonging their hospital stay and delaying recovery from metabolic acidosis.
The retrospective analysis reviewed medical records of children under 14 years admitted with DKA between 2021 and 2023. Of the 31 cases studied, 7 children (22.6%) developed AKI. The study aimed not only to identify the proportion and predictors of AKI in this population but also to assess its impact on clinical outcomes such as hospital stay and resolution of acidosis.
Speaking to Medical Dialogues about the motivation behind the study, Dr. Tadakanahalli shared, “We had a case of DKA in a child who developed AKI severe enough to require dialysis. That experience prompted us to explore the prevalence and predictors of AKI in children with DKA. The available literature showed wide variation in incidence, so we wanted to better understand the situation in our setting."
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