Acid-suppressants use during infancy increases childhood risk of recurrent wheeze and asthma
Massachusetts: A cohort study of children with a history of severe bronchiolitis found that the use of acid-suppressant medications during infancy increases the risk of recurrent wheeze and asthma during early childhood but is not associated with the risk of allergen sensitization in them. The article is published in The Journal of Allergy and Clinical Immunology: In Practice.
Bronchiolitis is a common respiratory infection among infants usually caused by the respiratory syncytial virus (RSV). Bronchiolitis is a risk factor in infants for developing conditions such as recurrent wheezing and childhood asthma in early childhood. Acid-suppressant medications like proton pump inhibitors (PPIs) and histamine-2 receptor antagonists (H2RAs), commonly prescribed in infancy may further increase the risk of allergic disease.
Studies have shown that Infants who are hospitalized for severe bronchiolitis and receive acid-suppressant medications may be at risk of developing the allergic disease by age 3 years. Little is known about the relationship between ASM exposure and the risk of childhood asthma and atopic conditions.
Robinson LB, Harvard Medical School, Boston, MA and his colleagues conducted a study to examine the association between infant acid-suppressant medications exposure and risk for developing recurrent wheeze, allergen sensitization, and asthma in early childhood.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.