Conservative management of PDA in low birth weight neonates doesn't increases mortality: Study
According to recent research, investigators have found that restrictive threshold for management of PDA in VLBW neonates may not be associated with an increase in morbidity or mortality, and possibly would reduce the need for pharmacological treatment or surgical ligation, as published in the Indian Pediatrics.
A hemodynamically significant patent ductus arteriosus (PDA) in preterm neonates is considered a risk factor for mortality, and morbidities such as bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), and intraventricular hemorrhage (IVH). A causal relationship between PDA and these adverse outcomes; however, has not been established.
Recent observational studies suggest that PDA closes spontaneously in most preterm neonates and use of a conservative approach for its management does not result in an increase in morbidity or mortality. Hence, Manoj Modi and colleagues from the Department of Neonatology, Sir Ganga Ram Hospital, New Delhi, India carried out the present study to compare outcomes of very low birth weight (VLBW) neonates before and after the change in practice for the treatment of PDA.
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