High intake of cow milk products increases risk of type 1 diabetes in kids: Study

Type 1 diabetes is more common among children in Finland than anywhere else in the world, and its incidence has multiplied manyfold since the 1950s.

"In terms of composition, milk is a very complex substance, and the factors in milk that may be associated with risk of diseases cannot be pinpointed on the basis of the research conducted so far," Koivusaari says.

That high consumption of milk in early childhood may potentially predispose people to type 1 diabetes has already been observed in prior studies.

A link between infant formula and asthma in children?

In addition to type 1 diabetes, Koivusaari investigated the link between cow's milk products and the development of asthma in children. The study found that the consumption of milk products subjected to high-temperature treatment, such as infant formula, was associated with a heightened risk of developing asthma. A corresponding link was not observed in pasteurized milk products, in which case the treatment is less intense. The findings indicate that the processing of milk may alter its immunological properties.

With regard to asthma, prior research has provided indications of raw, unprocessed milk potentially protecting children against asthma. However, raw milk cannot be recommended for children, as it may contain hazardous bacteria. Koivusaari's doctoral thesis is the first study observing a possible link between the high consumption of milk products subjected to high-temperature treatment, which includes infant formula, and a heightened risk of developing asthma in children.

According to Koivusaari, further research is needed to understand whether the consumption of cow's milk products actually predisposes to preclinical type 1 diabetes and that of infant formulas to asthma. It may also be that the explanation for the links observed is a factor that is yet to be identified.

"Further studies should also determine which factor in milk may be connected to the risk of diseases for this to be taken into account in its processing. Individual research findings do not change nutritional recommendations, which are based on extensive research evidence," Koivusaari notes.

The dataset

The dataset utilized in Koivusaari's doctoral thesis is based on the Type 1 Diabetes Prediction and Prevention (DIPP) study, which includes more than 6,000 children born between 1996 and 2004 in the university hospitals of Tampere and Oulu.

In the study, data on the children's diets were collected with the help of food records. Cow's milk products were classified according to the adopted heat treatment and homogenization. At intervals of 3–12 months, the study participants were monitored for the occurrence in blood samples of type 1 diabetes-related autoantibodies, which indicate prediabetes, and information on asthma was collected when the children were five.

Reference:

The study titled, "Consumption of differently processed milk products and the risk of asthma in children," was published in the journal Pediatric Allergy and Immunology.

DOI: https://onlinelibrary.wiley.com/doi/10.1111/pai.13659