Maternal Vitamin D deficiency associated with Autism in offsprings: Study
Insufficient or deficient maternal Vitamin D Levels are associated with Autism Spectrum Disorder (ASD) in their children suggests a new Study.This finding has implications for understanding the role of maternal vitamin D during fetal brain development and increased risk of ASD.
The study has been published in Biological Psychiatry.
Findings from previous studies on maternal 25-hydroxyvitamin D [25(OH)D] levels during pregnancy and autism spectrum disorder (ASD) in offspring are inconsistent.
The association between maternal 25(OH)D levels during pregnancy and offspring Autism Spectrum Disorder (ASD) was examined using data from a nationwide population-based register with a nested case-control study design. The Autism Spectrum Disorder (ASD) cases (n = 1558) were born between 1987 and 2004 and received a diagnosis of Autism Spectrum Disorder (ASD) by 2015; cases were matched with an equal number of controls. Maternal 25(OH)D levels during pregnancy were measured using quantitative immunoassay from maternal sera collected during the first and early second trimesters and archived in the national biobank of the Finnish Maternity Cohort. Conditional logistic regression examined the association between maternal 25(OH)D levels and offspring Autism Spectrum Disorder (ASD).
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