More than 80% of kids with low risk for sepsis received antibiotics, finds study
More than 80% of kids with low risk for sepsis received antibiotics, finds a study published in Pediatrics.
Multiple strategies are used to identify newborn infants at high risk of culture-confirmed early-onset sepsis (EOS). Delivery characteristics have been used to identify preterm infants at the lowest risk of infection to guide the initiation of empirical antibiotics. The researcher's objectives were to identify term and preterm infants at the lowest risk of EOS using delivery characteristics and to determine antibiotic use among them.
This was a retrospective cohort study of term and preterm infants born January 1, 2009, to December 31, 2014, with blood culture with or without cerebrospinal fluid culture obtained ≤72 hours after birth. Criteria for determining low EOS risk included: cesarean delivery, without labour or membrane rupture before delivery and no antepartum concern for intraamniotic infection or no reassuring foetal status. The researchers determined the association between these characteristics, the incidence of EOS, and antibiotic duration among infants without EOS.
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