Prenatal exposure to diurnal temperature variation linked to development of childhood pneumonia, Study says
Recent research published in the BMC Pediatrics Journal has revealed that preconceptional and prenatal exposure to DTV plays an important role in development of childhood pneumonia, especially during the first and second trimesters of pregnancy.
Pneumonia is the leading cause of death and hospitalization among young children worldwide, but its risk factors remain unclear.
Hence, Xiangrong Zheng and associates from the Department of Pediatrics, XiangYa Hospital, Central South University, Changsha, Hunan, China conducted the present study to evaluate the effect of maternal exposure to diurnal temperature variation (DTV) during preconceptional and prenatal periods on childhood pneumonia.
The authors conducted a retrospective cohort study by case-control design for pneumonia (N = 699) and normal (N = 811) children under age of 14 who were enrolled in XiangYa Hospital, Changsha, China. Demographic data including gender, age, birth season, gestational age, parity, mode of delivery, and parental atopy were collected from the electronic medical records in the hospital system.
The investigators obtained the data of daily DTV and the maternal exposure to DTV during preconceptional and prenatal periods was respectively calculated by the average of daily DTV during one year and three months before conception and entire pregnancy as well as the three trimesters. The association between maternal exposure to outdoor DTV and childhood pneumonia was analyzed by multiple logic regression model.
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