Prenatal Syphilis Exposure Linked to Higher Hospitalization Risk in Children: JAMA
A new study published in the Journal of American Medical Association found that children exposed to syphilis during pregnancy, even without congenital infection at birth, faced increased risk of hospital admissions and longer hospital stays. The study highlighted the need for close follow-up and prevention efforts in women of childbearing age.
The long-term consequences and effects on children exposed to syphilis during pregnancy but without a congenital infection identified at birth are still unknown, despite the fact that the short-term effects of congenital syphilis are well established. Thus, to examine the rates of hospitalization for all causes in children under five years old between those who were exposed to syphilis during pregnancy (with or without congenital syphilis) and those who were not, Enny Paixão and her colleagues carried out this study.
This population-based study included singleton live births from January 1, 2011, to December 31, 2015, after utilizing linked data from the Center of Data and Knowledge Integration for Health Birth Cohort. Until they turned five, passed away, or died on December 31, 2018, the children were monitored. Between March and September 2024, data that had been made public in 2020 were examined. Maternal syphilis, congenital syphilis, and no exposure, for individuals lacking syphilis records, were the three categories into which syphilis during pregnancy was divided in this study.
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