Rare case of neonatal arrhythmias in Turner syndrome reported in EHJ
Dr Meena Bolourchi, MD, assistant professor of pediatrics at Boston University School of Medicine and colleagues have reported a rare case of heart rhythm problem in newborn with Turner syndrome.The case has appeared online in the European Heart Journal.
Doctors treating babies born with Turner syndrome need to look for heart rhythm abnormalities, in addition to the usual heart problems of high blood pressure or left-sided structural heart defects, according to Meena Bolourchi, MD, assistant professor of pediatrics at Boston University School of Medicine.
In the general newborn population, cardiac arrhythmias occur in approximately 24.4 per 100,000 live births and may occur with or without congenital heart disease. The most common arrhythmia is supraventricular tachycardia (SVT) (abnormally fast heart rate coming from the top chambers of the heart) with an incidence of one per 250 to one per 1,000 pediatric patients depending on the source. Atrial flutter occurs less often, with an incidence of 2.1 per 100,000 live births and typically does not reoccur after treatment. While one study of newborns with atrial flutter showed that 25 percent had a second atrial arrhythmia, none of them had an underlying genetic syndrome.
To date, there had been no known associations between Turner syndrome and the development of atrial flutter with or without SVT. Bolourchi stresses that if a baby or child has been diagnosed with Turner syndrome, it would be important to look for heart rhythm abnormalities, in addition to the usual heart problems of high blood pressure or left-sided structural heart defects.
"This case illustrates that infants and children with Turner syndrome may be at risk for cardiovascular rhythm disorders, such as atrial flutter or supraventricular tachycardia. "Early and precise investigation of such cardiac abnormalities is important to reduce morbidity and mortality of these patients," adds Bolourchi, a pediatric cardiologist at Boston Medical Center.
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