Research alert: CBD might help children with autism, but more research needed

Researchers at the Center for Medicinal Cannabis Research at University of California San Diego School of Medicine have found that cannabidiol (CBD), a non-intoxicating compound found in cannabis, could help reduce problematic behaviors in autistic boys. The results provide valuable insights into the potential benefits and limitations of CBD as a therapeutic intervention for autism.

Autism spectrum disorder is a complex neurodevelopmental condition characterized by social communication difficulties, repetitive behaviors and restricted interests. In more severe cases, these behaviors can also include self-injury or aggression. While existing treatments can help manage these symptoms, there is a pressing need for effective and safe interventions to address the diverse needs of autistic individuals.

Some prior studies have suggested that CBD could help reduce problematic behaviors in children with autism. However, no controlled clinical trials have addressed safety, tolerability and efficacy of this treatment approach until now.

In the trial, autistic boys with severe behavior problems aged 7–14 years were split into two groups. One received eight weeks of daily CBD then eight weeks of placebo, separated by a four-week “washout” period in which no treatment was given. The other group received placebo first, then CBD. Behavioral assessments were completed before and after each treatment phase. A total of 30 participants completed the trial.