Antipsychotic drugs usage may contribute to development of breast cancer
China: A new study published in Epidemiology and Psychiatric Sciences shows that the prolactin-raising effects of certain drugs may be responsible for the modest link between antipsychotic usage and breast cancer.
Despite claims that antipsychotic usage in women increases the incidence of breast cancer, the available research is still ambiguous. As a result, this study was carried out by Janice Ching Nam Leung and colleagues to investigate the observational data already present in the literature and establish this hypothesized link.
The key findings of this study are summarized below:
1. Ultimately, nine observational studies were considered for review (N = 2 031 380) and seven for meta-analysis (N = 1 557 013), comprising five cohorts and four case-control studies.
2. All of the studies that were included received good marks (seven to nine stars). Antipsychotic usage was found to be significantly associated with breast cancer in six studies.
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