Bipolar Disorder Associated with High Risk of PCOS: Study
A recent study led by Jieyu Liu discovered a significant association between bipolar disorder (BD) and polycystic ovary syndrome (PCOS), unraveling the complex interplay between mental health and endocrine disturbances. The findings were published in the Journal of Affective Disorders.
With 72 drug-naïve BD patients, 98 healthy controls, and 72 BD patients on long-term medication, this study revealed that drug-naïve BD individuals exhibited a threefold higher prevalence of PCOS compared to their healthy counterparts, even after accounting for demographic factors (Odds Ratio: 3.02, 95% CI: 1.09–8.36).
The research delved into the impact of specific medications on PCOS within the BD population. Long-term treatment with valproate, a commonly prescribed mood stabilizer, was found to be a significant factor correlated with the increased occurrence and development of PCOS in BD patients (Odds Ratio: 3.89, 95% CI: 1.13–13.37).
The study also identified age and the insulin resistance index as additional factors influencing the prevalence of PCOS in BD patients, emphasizing the multifaceted nature of this association.
Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.
NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.