Bright Light Therapy Proves Effective for Nonseasonal Depressionan, Shows JAMA study

Researchers have found the use of bright light therapy (BLT) as an adjunctive treatment in patients with nonseasonal depressive disorders. A recent systematic review and meta-analysis claimed that BLT has shown significant improvements in terms of remission and response rates over standard treatments such as antidepressant monotherapy or dim red light therapy in these patients. This study was published in JAMA Psychiatry by Artur M. and colleagues..
Researchers conducted a broad search of the MEDLINE, Embase, and Cochrane databases on RCTs published between 2000 and March 2024. Information in eleven trials summarizing the data of 858 patients was included in the meta-analysis, of whom 649 were female (75.6%). The analysis compared the effects of BLT with dim red light therapy or antidepressant monotherapy. The Mantel-Haenszel method was used to compare the differences in treatment-related outcomes, and heterogeneity was quantified using I2 statistics.
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