Capnometry Guided Respiratory Intervention reduced panic and stress levels of PTSD patients: Frontiers

A new study published in Frontiers in Digital Health showed that a considerable rate of symptom reduction and adherence was noticed in 1,569 patients who received Capnometry Guided Respiratory Intervention (CGRI) with respect to panic and stress.

Capnometry Guided Respiratory Intervention, a prescription digital therapeutic for the treatment of panic disorder (PD) and post-traumatic stress disorder, has consistently demonstrated clinical benefit in earlier clinical trials. As a result, Robert N. Cuyler and colleagues carried out this study with the intention of reporting actual results in a number of patients who received the intervention in clinical practice.

In a large real-world series of patients receiving CGRI for panic disorder and PTSD, this research offers pre- and post-treatment self-reported symptom reduction, measurements of respiration rate and end-tidal carbon dioxide levels, drop-out and adherence rates taken from an automated data repository. Patients implemented the intervention at home with telehealth coaching's assistance. Following evaluation by a healthcare professional, patients with panic disorder (n = 1,395) or posttraumatic stress disorder (n = 174) who met the symptom criteria were treated. Pre- and post-treatment scores on the self-reported Posttraumatic Stress Disorder Checklist for DSM-5 (PCL-5) and Panic Disorder Severity Scale (PDSS) were obtained.