Gabapentin effective treatment option for alcohol use disorder: JAMA
About 30 million people in the U.S. meet criteria for alcohol use disorder, yet less than 1 million receive medication that may be beneficial.
The researchers conducted a randomized clinical trial to investigate if gabapentin, a drug often used to treat nerve pain, would be useful in the treatment of patients with alcohol use disorder and a history of alcohol withdrawal symptoms.
They have found that Gabapentin appears to be efficacious for the treatment of alcohol use disorder (AUD), especially among those with high alcohol withdrawal.The study has been published in JAMA Internal Medicine.
In the study total of 145 treatment-seeking individuals with AUC were screened, and 96 who also met recent alcohol withdrawal criteria were randomly assigned to treatment with gabapentin versus placebo after three abstinent days. Ninety of the participants were evaluable: 44 and 46 in the gabapentin and placebo arms, respectively.
The percentage of individuals with no heavy drinking days and those with total abstinence were compared between treatment groups and further evaluated based on prestudy alcohol withdrawal symptoms.
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