Long-Term Study reveals high Incidence of depression in patients after Stroke

The key findings of the study were:

• The cumulative incidence of PSD over 18 years was 59.4%, with 87.9% of cases occurring within the first 5 years post-stroke.

• Within 3 months, 33.4% of PSD cases were identified, increasing to 54.6% within 1 year.

• Recurrence of depression was common, with 66.7% of patients experiencing recurrence, predominantly within 5 years of recovery.

• Patients with severe depression had lower recovery rates and higher recurrence rates compared to those with mild depression.

• Routine screening for depression within 5 years post-stroke is recommended, as depression can begin as early as 3 months post-stroke.

The study highlights the significant burden of PSD in stroke survivors and underscores the need for long-term monitoring and support. Early detection and intervention for depression can improve outcomes and enhance the overall well-being of stroke survivors.

Post-stroke depression is prevalent, with the majority of cases occurring within the first 5 years post-stroke. Routine screening for depression in stroke survivors is crucial for timely identification and management of this common complication. Long-term follow-up and support are essential to address the high recurrence rates observed in this population.

Reference:

Liu L, et al "Natural history of depression up to 18 years after stroke: a population-based South London Stroke Register study" Lancet Reg Health Eur 2024; DOI: 10. 1016/j.lanepe.2024. 100882.