Overweight or obese adults more prone to depression: Study
Researchers have found in a new study that the risk of depression also rose with higher weight, according to Obesity analysis.
Researchers conducted a study to describe the age‐ and gender‐specific incidence of depression, the dose‐response relationship between BMI and risk of depression and antidepressant drug prescribing in adults with overweight or obesity.
They studied electronic health record retrospectively using the Clinical Practice Research Datalink to identify adults with overweight and obesity (≥ 18 years) with incident depression (no prior depression diagnosis in their records), followed up from 2000 to 2019.
In an analysis of primary care records of 519,513 UK adults who were overweight or obese between 2000–2016 and followed up until 2019, the incidence of new cases of depression was 92 per 10,000 people per year.
The study also found that antidepressants were prescribed in approximately two-thirds of adults who were overweight or obese. Prescriptions for fluoxetine dropped over time (from 20.4% in 2000 to 8.8% in 2018) and prescriptions for sertraline increased (from 4.3% in 2000 to 38.9% in 2018).
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