Unsupervised home-use of transcranial direct current fails to improve major depression: JAMA
Transcranial direct current stimulation (tDCS) is moderately effective in treating depression when administered by trained professionals. However, it remains unclear whether self-administered tDCS, either alone or in combination with a digital psychological intervention, is also effective in treating depression.
According to an Original Investigation published in JAMA Psychiatry, Unsupervised home-use transcranial direct current stimulation (tDCS) along with a digital psychological intervention or a digital placebo demonstrates no superiority compared to sham treating individuals with major depressive episodes.
In this randomized clinical trial involving 210 adults with a major depressive episode, no significant differences were found between home-use tDCS combined with either a digital psychological intervention or digital placebo and sham in reducing depressive symptoms after six weeks. The aim was to determine whether fully unsupervised home-use tDCS, combined with a digital psychological intervention or digital placebo, is effective for treating major depressive episodes.
doi:10.1001/jamapsychiatry.2023.4948
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