Chronic rhinosinusitis risk closely connected with frailty, slowness and emotional tiredness: Study

A new study published in the journal of The Laryngoscope showed that, there is a connection between frailty and chronic rhinosinusitis (CRS), which may be brought on by emotional tiredness and slowness. This suggests that in order to control the occurrence of CRS, effective therapies for avoiding frailty should be created.

One of the most prevalent chronic illnesses affecting people in the US is chronic rhinosinusitis (CRS), which is characterized by symptoms of inflammation of the sinonasal mucosa that last for at least 12 weeks. Chronic rhinosinusitis without nasal polyposis (CRSsNP) and chronic rhinosinusitis with nasal polyposis (CRSwNP) are the two distinct phenotypes into which CRS is usually clinically divided. With disease-specific costs of almost $6 billion a year, patients with CRS experience a markedly reduced quality of life, including diminished health usefulness, mental anguish, and decreased physical and social activities. Despite ongoing research into the pathophysiology of CRS, the etiology of the condition is still up for debate. In this study, Han Chen and team used a representative sample from the Korean population to examine the relationship between chronic rhinosinusitis and frailty.

A total of 24,269 people participated in this cross-sectional study at first, and the Korean National Health and Nutrition Examination Survey (KNHANES) database provided the data. Using criteria specifically designed for the KNHANES dataset, the modified frailty phenotype (FP) and frailty index (FI) were used to measure frailty. The self-reported medical histories of participants were used to identify CRS. To investigate the relationship between CRS and frailty, univariate and multivariate logistic regression models were used.