Constipation linked to survival of patients with idiopathic interstitial pneumonias, finds study
A new study published in the journal of Respiratory Investigation showed that constipation may have therapeutic value since it is an independent predictive factor for individuals with idiopathic interstitial pneumonias (IIPs). Idiopathic pulmonary fibrosis (IPF), the most common phenotype of IIPs, has a prognosis that is influenced by a number of clinical variables, including age, sex, dyspnea, body mass index (BMI), smoking status, pulmonary function, and radiological abnormalities. The prognosis of many chronic illnesses is impacted by constipation that lowers quality of life. According to reports, people who have constipation are more likely than those who do not to suffer from coronary heart disease, ischemic stroke, and all-cause death. According to a meta-analysis, children who had constipation were more likely to acquire asthma later on.
The impact of constipation on the prognosis of IIPs is yet unknown, though. Basic research has indicated that the gut microbiota may have an impact on pulmonary fibrosis, despite the fact that IIPs are chronic inflammatory illnesses with an uncertain cause. As with other chronic conditions, constipation may have a correlation with the prognosis of IIPs. Thus, Sho Takuma and colleagues used a time-dependent multivariate analysis that was controlled for clinical variables in the current investigation to examine the relationship between constipation and the prognosis of patients with IIPs.
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