Does nafamostat reduce death in COVID-19 patients? Study sheds light
Written By : Medha Baranwal
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-10-26 04:30 GMT | Update On 2023-10-26 06:38 GMT
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Australia: The researchers found a 93% posterior probability that nafamostat reduced the odds of death or organ support among hospitalized patients with COVID-19. The findings from the study were published online in NEJM Evidence on October 18, 2023.
Nafamostat mesylate is a potent in vitro antiviral agent that inhibits the host transmembrane protease serine 2 enzyme used for cell entry by the severe acute respiratory syndrome coronavirus 2. Steven Y.C. Tong, Victorian Infectious Diseases Service, The Royal Melbourne Hospital, Melbourne, VIC, Australia, and colleagues conducted an open-label, pragmatic, randomized clinical trial in New Zealand, Australia, and Nepal.
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