Heavy alcohol intake may increase risk of developing tuberculosis in Diabetes patients: Study
Heavy alcohol intake may increase the risk of developing tuberculosis in Diabetes patients suggests a study published in the respiratory research.
Diabetes mellitus (DM) and alcohol consumption are risk factors for tuberculosis (TB). We investigated the association between alcohol consumption and TB development in individuals with type 2 DM (T2DM).
Individuals who underwent the national health examination during 2009–2012 were screened using the Korean National Health Information Database. In total, 2,437,443 eligible individuals with T2DM were followed up until December 2018. We identified 21,275 individuals with newly developed TB. Alcohol consumption was evaluated based on the health examination questionnaire, and individuals were categorized into none (0 g/day), mild-to-moderate (1–29.9 g/day), and heavy (≥ 30 g/day) drinkers.
Multivariate Cox proportional hazard models were used to estimate the adjusted hazard ratio (aHR) of risk factors for TB. Results: Mild-to-moderate alcohol drinkers had a lower risk of developing TB (aHR 0.92, 95% confidence interval [CI] 0.89–0.96), and heavy alcohol drinkers had a higher risk of developing TB (aHR 1.21, 95% CI 1.16–1.27) than nonalcohol drinkers. When categorized by an alcohol intake of 5 g/day, alcohol drinkers of < 5 g/day had the lowest risk (aHR 0.85, 95% CI 0.81–0.90).
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