High intake of niacin linked to enhanced lung function and lower COPD risk

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2024-02-15 22:00 GMT | Update On 2024-02-16 06:49 GMT

High intake of niacin linked to enhanced lung function and lower COPD risk suggests a new study published in the Scientific Reports.

Chronic obstructive pulmonary disease (COPD) is a prevalent lung condition, primarily characterized by airflow obstruction resulting from abnormalities in the airways and alveoli. Evidence regarding the association between dietary niacin intake and chronic obstructive pulmonary disease (COPD) is limited. The study investigates the relationship between dietary niacin intake and the prevalance and incidence of COPD in the adult population of the United States, using data from the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2018. Data on niacin intake were extracted through dietary intake interviews. COPD diagnoses were based on lung function, medical history, and medication usage. We analyzed the association between niacin consumption and COPD using multiple logistic regression and restricted cubic spline models.

The study included 7055 adult participants, divided into COPD (n = 243; 3.44%) and non-COPD (n = 6812; 96.56%) groups. Those with COPD had lower average niacin intake (21.39 ± 0.62 mg/day) compared to the non-COPD group (25.29 ± 0.23 mg/day, p < 0.001). In the adjusted multivariable model, the odds ratios (OR) and 95% confidence intervals (CI) for COPD in the highest versus lowest quartile of dietary niacin intake were 0.55 (0.33 to 0.89, P for trend = 0.009). Subgroup analysis, after adjustment for various variables, revealed no significant interaction effects. Dietary niacin intake was inversely associated with COPD prevalence in US adults. Participants with the highest dietary niacin intake demonstrated the lowest odds of COPD. The potential of dietary niacin supplementation as a strategy to mitigate COPD warrants further investigation.

Reference:

Li, WW., Ren, KL., Yu, J. et al. Association of dietary niacin intake with the prevalence and incidence of chronic obstructive pulmonary disease. Sci Rep 14, 2863 (2024). https://doi.org/10.1038/s41598-024-53387-4

Article Source : Scientific Reports

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Dr. Shravani Dali

Dr. Shravani Dali has completed her BDS from Pravara institute of medical sciences, loni. Following which she extensively worked in the healthcare sector for 2+ years. She has been actively involved in writing blogs in field of health and wellness. Currently she is pursuing her Masters of public health-health administration from Tata institute of social sciences. She can be contacted at editorial@medicaldialogues.in.

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High intake of niacin linked to enhanced lung function and lower COPD risk

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