Hospitalized patients with RSV infections are at higher risk of mortality, finds study

After controlling for covariates, this multicenter observational cohort study examined the clinical symptoms, mortality risk factors and correlation with 90-day mortality by logistic regression analysis among persons hospitalized with RSV or influenza A or B between March 2016 and April 2020. Out of the 988 patients that were admitted to the hospital, 353 had RSV, 288 had influenza B and 347 had influenza A. Patients with RSV were more likely to have pneumonia and comorbidities when compared to influenza A and B. RSV infection was linked, relative to influenza B infection but not influenza A infection, to a higher all-cause mortality within 90 days after covariate correction. In patients with RSV, becoming older and having pneumonia at the time were found to be independent risk factors for death. Overall, RSV-induced acute respiratory infections cause considerable morbidity and death in older persons.

Source:

Clausen, C. L., Egeskov-Cavling, A. M., Hayder, N., Sejdic, A., Roed, C., Gitz Holler, J., Nielsen, L., Eiberg, M. F., Rezahosseini, O., Østergaard, C., Barrella Harboe, Z., K Fischer, T., Benfield, T., & Lindegaard, B. (2024). Clinical manifestations and outcomes in adults hospitalized with respiratory syncytial virus and influenza A/B: A multicenter observational cohort study. In Open Forum Infectious Diseases. Oxford University Press (OUP). https://doi.org/10.1093/ofid/ofae513