Hyaluronic acid may predict severity & prognosis of community-acquired pneumonia: Study
Hyaluronic acid (HA) has emerged as a promising biomarker for assessing the severity & prognosis of community-acquired pneumonia (CAP), showing strong diagnostic accuracy (AUC: 0.709) as published in the Journal of Inflammation Research.
Hyaluronic acid (HA) is a novel inflammatory biomarker with a prognostic value for several infectious diseases. This study investigated the association of Hyaluronic acid with severity and prognosis in hospitalized patients with community-acquired pneumonia (CAP).
They analyzed the differences of Hyaluronic acid levels in different groups. Logistic regression analysis was performed to identify independent risk factors for severe CAP (SCAP). The predictive value of Hyaluronic acid for SCAP was assessed using receiver operating characteristic (ROC) curves. Kaplan-Meier survival analysis was used to compare 30-day mortality between the high and low Hyaluronic acid groups. Results: Compared to healthy controls (49.2 ± 15.3 ng/mL), patients with CAP exhibited significantly elevated levels of Hyaluronic acid(P < 0.001).
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