ICS use safe in kids with asthma, no evidence of suppression of Hypothalamic-Pituitary-Adrenal Axis
Jodhpur, Rajasthan: Inhaled corticosteroids are considered the most effective treatment for children with persistent asthma. However, adverse effects of ICS on the Hypothalamic Pituitary Adrenal axis, growth and bone metabolism are a concern.
A recent study published in the Indian Journal of Pediatrics has suggested inhaled corticosteroids (ICS) to be a safe drug in children for asthma treatment, even for the long term.
The study showed that a few children had low post-adreno-corticotropic hormone (ACTH) stimulation cortisol value, and none had clinical evidence of hypothalamic-pituitary-adrenal (HPA) axis suppression.
The study was conducted by Prawin Kumar, All India Institute of Medical Sciences (AIIMA), Jodhpur, Rajasthan, India, and colleagues to evaluate the effect of the long-term use of inhaled corticosteroids on the hypothalamic-pituitary-adrenal axis.
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