Increased risk of bronchiectasis observed in individuals with rheumatoid arthritis
In a recent study published in the journal of CHEST analyzed the coexistence of bronchiectasis and rheumatoid arthritis (RA) by revealing that individuals with RA face a two-fold higher risk of developing bronchiectasis when compared to individuals without this inflammatory joint disorder.
The study was conducted with a group of 50,651 individuals with RA (35,879 seropositive RA [SPRA] and 14,772 seronegative RA [SNRA]) with carefully matched control group of 253,255 participants to investigate the relationship between RA and bronchiectasis.
Over a median follow-up period of 4.3 years the individuals with RA exhibited a cumulative incidence of bronchiectasis at approximately 7%, which prompts a concern about the intricate interplay between these conditions.
After meticulous adjustment for potential confounders related to bronchiectasis this research unveiled that participants with RA bore a 2.12-fold higher risk of developing bronchiectasis when compared to their matched counterparts (95% confidence interval [CI], 2.00–2.25). This suggests that beyond the shared risk factors, rheumatoid arthritis itself contributes to the increased susceptibility to bronchiectasis.
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