Non-invasive electromagnetic phrenic nerve stimulation in ICU Setting Key to Preventing Diaphragm Atrophy: CHEST

Written By : Aditi

Medically Reviewed By : Dr. Kamal Kant Kohli

Published On 2024-03-27 13:30 GMT | Update On 2024-03-27 13:30 GMT

Electromagnetic stimulation of the phrenic nerve induces diaphragm contractions, but no coils for clinical use have been available.

In original Research published in CHEST, researchers concluded that Bilateral transcutaneous non-invasive electromagnetic phrenic nerve stimulation (NEPNS) has proven to be a feasible option in the intensive care unit (ICU) setting, potentially offering the advantage of preventing diaphragm atrophy during mechanical ventilation. However, they added that further evaluation of NEPNS ventilation effectiveness is necessary.

This study evaluated the feasibility of using 15-minute bilateral transcutaneous neurostimulation (NEPNS) in patients intubated for at least 72 hours. The intervention group received NEPNS twice daily for 15 min, while the control group received standard care. The primary outcome measure was the time to find the optimal stimulation position, and the secondary endpoint assessed expiratory diaphragm thickness using ultrasound.

Key findings from the study are:

• The revised EU regulation mandated the reapproval of medical devices, prematurely halting the study. Eleven patients were enrolled, including five interventions and six controls.

• The time to find an adequate stimulation position was 23 seconds.

• The intervention twice daily was executed in 87% of cases, and 92% included a next-day catch-up session.

• Ventilation with 3-6ml/kgIBW was achieved in 43 % of stimulations with stimulation only and 62 % with additional pressure support.

• Bilateral NEPNS prevented the decrease in diaphragm thickness until day 10.

This study demonstrated the feasibility of bilateral transcutaneous NEPNS in critical care, with a successful deployment rate of 23 seconds and a high realization rate of over 90% of planned sessions. STIMIT AG, Biel, Switzerland, supported the study.

Reference:

Panelli A, Grimm AM, Krause S, Verfuß MA, Ulm B, Grunow JJ, Bartels HG, Carbon NM, Niederhauser T, Weber-Carstens S, Brochard L, Schaller SJ, Non-invasive electromagnetic phrenic nerve stimulation in critically ill patients – a feasibility study., CHEST (2024), doi https:// doi.org/10.1016/j.chest.2024.02.035.

Article Source : CHEST

Disclaimer: This website is primarily for healthcare professionals. The content here does not replace medical advice and should not be used as medical, diagnostic, endorsement, treatment, or prescription advice. Medical science evolves rapidly, and we strive to keep our information current. If you find any discrepancies, please contact us at corrections@medicaldialogues.in. Read our Correction Policy here. Nothing here should be used as a substitute for medical advice, diagnosis, or treatment. We do not endorse any healthcare advice that contradicts a physician's guidance. Use of this site is subject to our Terms of Use, Privacy Policy, and Advertisement Policy. For more details, read our Full Disclaimer here.

NOTE: Join us in combating medical misinformation. If you encounter a questionable health, medical, or medical education claim, email us at factcheck@medicaldialogues.in for evaluation.

Aditi

Dr. Aditi Yadav is a BDS, MDS in Periodontics and Implantology. She has a clinical experience of 5 years as a laser dental surgeon. She also has a Diploma in clinical research and pharmacovigilance and is a Certified data scientist. She is currently working as a content developer in e-health services. Dr. Yadav has a keen interest in Medical Journalism and is actively involved in Medical Research writing.

Comments Policy

Our comments section is governed by our Comments Policy . By posting comments at Medical Dialogues you automatically agree with our Comments Policy , Terms And Conditions and Privacy Policy .

Non-invasive electromagnetic phrenic nerve stimulation in ICU Setting Key to Preventing Diaphragm Atrophy: CHEST

Similar News

Breathing Trouble: Meta-Analysis Links Inhaled Pollutants to Higher Risk of GERD, Ulcers, and GI Cancers

Incorporating Chest CT and Symptoms into COPD Diagnostic Criteria may identify individuals with poor outcomes: JAMA

USFDA grants priority review for Winrevair label update based on ZENITH Trial: Merck

Adult Asthma Linked to Higher Risk of Multiple Comorbidities Over 15 Years: Study

Moderate Increase in Dementia Risk Linked to Tiotropium Use in Older COPD Patients: JAMA

NLR Shows Promise in Asthma Detection and Severity Stratification: Meta-Analysis

Night Shifts Linked to Increased Asthma Risk in Postmenopausal Women: Study

Medical Bulletin 01/Jul/2025