Paxlovid and Molnupiravir Reduce Mortality and Hospitalisation in High-Risk Omicron-Infected Patients
Written By : Dr Riya Dave
Medically Reviewed By : Dr. Kamal Kant Kohli
Published On 2023-09-23 06:00 GMT | Update On 2023-09-23 06:03 GMT
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Ritonavir-boosted Nirmatrelvir and Molnupiravir, two oral antiviral drugs currently used to treat nonhospitalized COVID-19 patients at high risk of progressing to severe disease, have not been extensively studied for their effectiveness against new SARS-CoV-2 Omicron sub variants, particularly BQ.1.1 and XBB.1.5. To address this, a cohort study published in JAMA Network Open by Dan-Yu Lin and colleagues was conducted among COVID-19 patients diagnosed at the Cleveland Clinic between April 1, 2022, and February 20, 2023. These patients were assessed for high-risk factors and followed up for 90 days after diagnosis as the Omicron variant evolved through various sub variants.
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