Pseudomonas aeruginosa Infection linked with Antibody-Mediated Rejection in Lung Transplant Recipients, suggests study
Lung transplant recipients are highly vulnerable to infections, with Pseudomonas aeruginosa being a leading cause of bacterial pneumonia. Researchers have found in a new study that infection with P. aeruginosa independently predicts antibody-mediated rejection (AMR) in these patients. Further early detection of such infections is suggested as a potential strategy for predicting and managing AMR, helping to develop effective prevention and treatment approaches. This study was published in the journal Science Translational Medicine by Fuyi L. and colleagues.
Lung transplant patients are at very high risk of developing bacterial pneumonia, and a common cause was P. aeruginosa. To verify this, an observational study was conducted on retrospective analysis to establish a relation between Pseudomonas infection and AMR. The presence of such correlation was especially clear in cystic fibrosis, who are considered to be susceptible to chronic Pseudomonas colonization.
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