Psoriasis patients at increased risk of COPD prevalence and incidence: Study

A new analysis of key findings on prevalence of chronic obstructive pulmonary disease (COPD) among patients with psoriasis identified a possible link between pulmonary disease and psoriasis, found that those with psoriasis have increased COPD prevalence and incidence,and that psoriasis is not shown to be an independent COPD risk factor. These findings and others represented the conclusion of new research conducted to improve understanding of the connection between COPD and psoriasis. These findings may, in turn, help to enhance methods of condition management. This analysis was led in part by Lily Guo, BS, of Duke University’s School of Medicine in Durham, North Carolina. Guo and colleagues noted that COPD is known to lead to diffuse pulmonary inflammation as well as potentially high rates of mortality. Understanding the relationship between psoriasis and chronic obstructive pulmonary disease (COPD) may enhance disease management.

They aimed to determine the (1) prevalence and (2) incidence and risk of COPD in psoriasis patients. Results: The COPD prevalence was 9.64% in psoriasis patients and 6.94% in psoriasis-free patients. The COPD incidence was 10.74 per 1000 person-years in psoriasis patients and 6.36 per 1000 person-years in psoriasis-free patients. Multivariable Cox regression showed no association between psoriasis and COPD development (HR 0.99, p = 0.271). The findings suggest that psoriasis is not an independent risk factor for COPD development.

Reference:

Guo L, Bilimoria SN, Kikuchi R, Hao A, Tolson H, Yamamoto RK, Sadrolashrafi K, Yee D, Armstrong AW. Prevalence, Incidence, and Risk of Chronic Obstructive Pulmonary Disease Among Psoriasis Patients. Respir Med. 2024 Jul 2:107729. doi: 10.1016/j.rmed.2024.107729. Epub ahead of print. PMID: 38964424.