Study Finds Association Between Lung Function and Incident Depression
China: In a groundbreaking study involving over 280,000 participants, researchers have discovered a significant association between lung function and the onset of depression. This prospective cohort study sheds light on the intricate biological pathways linking respiratory health to mental well-being.
The study, published in BMC Medicine, revealed that the higher risk of depression development was associated with impaired lung function. Moreover, the association might be mediated partially by biomarkers, including erythrocytes, systemic inflammation, and renal and liver function.
"In a cohort of patients with varying lung function assessed through values of forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV1), and no previous depression, participants with the lowest lung function had increased depression levels versus individuals with better levels of lung function," the researchers reported.
Lung health is increasingly being recognized as an important factor in mental health. However, there is a need to determine prospective evidence on lung function with incident depression. Considering this, Bao-Peng Liu, Cheeloo College of Medicine, Shandong University, Jinan, China, and colleagues aimed to examine the prospective association between impaired lung function and incident depression and the underlying biological mechanisms.
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