The research, led by Iris Burck from the Clinic for Radiology and Nuclear Medicine at University Hospital Frankfurt, highlights notable gains in sensitivity without compromising specificity, offering a promising enhancement to pre-treatment imaging.
The study evaluated MRI datasets from 40 patients diagnosed with stage III or IV oral squamous cell carcinoma between August 2020 and April 2023. All participants underwent two types of MRI scans—one using the standard 20-channel head-and-neck coil and another using a 15-channel dental coil designed specifically for imaging the oral cavity.
Two experienced radiologists independently assessed multiple parameters, including signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), bone infiltration, metal artefacts, overall image quality, and tumour delineation. These assessments were performed using a 5-point grading scale. The researchers also compared MRI findings with histopathological reports to determine diagnostic accuracy, while interobserver agreement was measured using Cohen’s kappa coefficients.
The study led to the following notable findings:
- The 15-channel dental coil showed significantly higher signal-to-noise ratio and contrast-to-noise ratio compared with the standard 20-channel coil.
- The contrast-to-noise ratio with the 15-channel coil was nearly 2.5 times greater, indicating improved contrast resolution.
- Image quality received higher ratings with the 15-channel coil (median 4.5 vs. 3).
- Radiologists observed better visualization of tumour margins, reduced metal artefacts, and more precise assessment of jaw infiltration using the 15-channel coil.
- All these improvements were statistically significant.
- Interobserver agreement was very high, with Cohen’s kappa values of 0.89 for bone infiltration assessment and 0.94 for overall image quality.
- Artefact reduction and lesion delineation also demonstrated substantial interobserver agreement.
- The 15-channel coil achieved 100% sensitivity in detecting histopathologically confirmed bone invasion, with only one false positive.
- The standard 20-channel coil missed six cases and produced three false positives.
- Both coils had similar specificity, but the 15-channel coil’s higher sensitivity makes it a more effective tool for pre-therapeutic imaging.
The study authors emphasized that improved visualization of tumour boundaries and bone involvement can play a crucial role in shaping individualized treatment plans. “MRI with a 15-channel dental coil provides superior image quality, lesion delineation, and bone infiltration detection in advanced oral cavity tumours,” they noted, adding that these capabilities support more precise and personalized cancer management.
The findings are especially relevant because detecting bone infiltration remains a significant challenge in oral cancer imaging. The enhanced spatial resolution offered by the dental coil could help clinicians stage disease more accurately and plan interventions more confidently.
"Overall, the study highlights the clinical value of adopting advanced, region-specific MRI coils to refine diagnostic accuracy in head and neck oncology," the authors concluded.
Reference:
Burck I, Liu X, Mahmoudi S, Scholtz JE, Lingwal N, Martin S, Koch V, Fleischmann M, Gotta J, Winkelmann R, Thoenissen P, Stöver T, Vogl TJ, Dos Santos DP. MR imaging with 15-channel dental coil compared with standard 20-channel coil in patients with head and neck tumours and suspected bone invasion. Eur J Radiol. 2025 Nov 24;195:112575. doi: 10.1016/j.ejrad.2025.112575. Epub ahead of print. PMID: 41319371.
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