Is FDG PET/MRI better than 18F-FDG PET/CT in diagnosing osteomyelitis: Study
In a new study published in the European Journal of Hybrid Imaging, suggests that 18F-FDG PET/MRI is an effective alternative to 18F-FDG PET/CT in the diagnosis of osteomyelitis.
In the complex diagnostic work-up of osteomyelitis, modalities including magnetic resonance imaging (MRI) and 2-[18F]-fluoro-2-deoxy-D-glucose (18F-FDG) positron emission tomography, coupled with computed tomography (PET/CT), are frequently utilized. Based on the opinions of experts and past qualitative research, PET/MRI is a relatively new hybrid modality with proposed uses in bone infection imaging. Compared to 18F-FDG PET/CT, 18F-FDG PET/MRI offers the benefits of a lower radiation dosage, more soft tissue data, and is thought to be more useful for surgical planning.
A nuclear medicine doctor and a radiologist retrospectively evaluated 36 patients who had 18F-FDG PET/MRI images for possible osteomyelitis. Sensitivity, specificity, and accuracy were assessed using the orthopedic surgeon's clinical evaluation as the gold standard (based on further intraoperative microbiology or long-term follow-up). Receiver operating characteristics (ROC) were used to measure and analyze standard uptake values (SUV).
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