Liquid biopsy improves MRI accuracy in breast cancer patients: Study
Italy: Liquid biopsy addition to MRI may improve the ability to measure treatment response of breast cancer, finds a recent study. The study findings were presented at the American Association for Cancer Research (AACR) annual meeting.
According to the study, in patients treated for localized breast cancer, measurement of plasma cell-free DNA (cfDNA) after chemotherapy and before surgery has the potential to improve MRI accuracy alone. This suggests a potential role of liquid biopsy for bolstering MRI which has suboptimal accuracy for this clinical use. There is a need for further and prospective evaluation.
Liquid biopsy's potential for improving the sensitivity of imaging has been an important area of cancer research in recent years.
Typically today, sentinel lymph node biopsy is performed to assess axillary node response after chemotherapy and is followed by lymph node dissection in those who do not have a complete response. A more accurate noninvasive method for gauging complete response and for monitoring could save some patients from the need for sentinel lymph node biopsy, the researchers noted.
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