Antibiotic-Loaded Hydrogel Does Not Compromise Hip Stem Stability, reports research
Researchers have discovered that an antibiotic-loaded hydrogel did not compromise the primary stability of uncemented hip stems. A biomechanical study recently proved that construct stiffness and stem subsidence in hip implants prepared with or without hydrogel were equivalent under varied load conditions. The study was conducted by Georgios and colleagues which was published in the journal BMJ Surgery.
The primary stability is considered the key determinant of success for uncemented hip implants because it influences long-term fixation. Antibiotic-loaded hydrogels, providing antimicrobial benefits without impacting stability, have been an area of interest and, therefore, required a comprehensive biomechanical assessment.
The primary stability was assessed using an electro-mechanic material test system (#5866, Instron, Norwood, MA, USA) provided with a 10-kN load cell. A quasi-static ramped compression loading protocol was applied at a rate of 0.005 mm/s. Six intermittent load levels from 500 N to 3000 N in steps of 500 N were used for testing.
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