Bursectomy not a recommended standard procedure for cT3-T4a gastric cancer
Japan Researchers found that bursectomy is not a recommended standard procedure for cT3-T4a gastric cancer in D2 gastrectomy in their phase III trial. The Trial results were published in the British Journal of Surgery.
A routine standard procedure in gastrectomy for resectable gastric cancer is the bursectomy where the total resection of the bursa omentalis is done. Researchers from various centers in Japan carried out a phase III trial (JCOG1001) comparing bursectomy and omentectomy alone. It was terminated early at the interim analysis and the final results of the updated analysis after a minimum follow-up of 5 years were reported by the researchers.
A multicenter randomized trial was carried out on patients with histologically proven adenocarcinoma of the stomach (cT3–T4a) between June 2010 and March 2015. They were randomized (1: 1) during surgery to bursectomy or omentectomy-alone groups and then underwent D2 gastrectomy. Nearly 1204 patients were randomized to the two groups having 602 patients in each. The primary endpoint was overall survival. The intention-to-treat basis was used to analyze the overall survival.
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