Continuing Antithrombic therapy safe during emergency lap chole for acute cholecystitis: Study
Continuing Antithrombic therapy (ATT) is safe during emergency laparoscopic cholecystectomy (LC) for acute cholecystitis (AC), according to a recent study published in the BMC surgery.
Acute cholecystitis is inflammation of the gallbladder. It usually happens when a gallstone blocks the cystic duct. Gallstones are small stones, usually made of cholesterol, that form in the gallbladder. Antithrombotic drugs in routine use include antiplatelet drugs (aspirin, clopidogrel, and glycoprotein IIb/IIIa receptor antagonists) and anticoagulants (unfractionated and low molecular weight heparin, warfarin, and direct thrombin inhibitors).
Continuing antithrombic therapy (ATT) during surgery increases the risk of bleeding. However, it is difficult to discontinue antithrombic therapy (ATT) in emergency surgery. Therefore, the safety of emergency laparoscopic cholecystectomy (LC) for acute cholecystitis (AC) is still unclear. We aimed to clarify the effect of antithrombic therapy (ATT) during emergency LC for AC.
Patients with AC were classified into antithrombic therapy (ATT) group (n = 30) and non- antithrombic therapy (ATT) group (n = 120). Postoperative outcomes were compared after propensity score matching (n = 22).
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